In recent years, due to the economic and environmental issues, modern power systems often operate proximately to the technical restraints enlarging the probable level of instability risks. Hence, efficient methods for voltage instability prevention are of great importance to power system companies to avoid the risk of large blackouts. In this paper, an event-driven emergency demand response (EEDR) strategy based on whale optimization algorithm (WOA) is proposed to effectively improve system voltage stability. The main objective of the proposed EEDR approach is to maintain voltage stability margin (VSM) in an acceptable range during emergency situations by driving the operating condition of the power system away from the insecure points. The optimal locations and amounts of load reductions have been determined using WOA algorithm. To test the feasibility and the efficiency of the proposed method, simulation studies are carried out on the IEEE 14-bus and real Algerian 114-bus power systems.