To solve the problems of overstep tripping, long action time and inapplicability after the integration of distributed generators (DGs) of the existing distribution line protection, a fast station-area protection of a distribution line and its implementation scheme are proposed. First, a topological model analysis method based on connection point path search is adopted, and a topological description model based on a one-way adjacency matrix is constructed to form a protection application topology matrix. Then, the characteristics of phase to phase faults and phase to ground faults of a multi-type DGs grid-connected system with random switching are analyzed, and the effective information of fault location are extracted to form the fault information matrix. The fault location matrix is generated by synthesizing topology and fault information and the fault location criteria are put forward. Finally, the protection device is designed and a test is carried out based on the RTplus platform. The results show that the protection action time does not exceed 60 ms while different types of faults occur at different positions of the distribution line and the tripping command is received by the target terminal unit to make the corresponding circuit breaker trip. Both the speed and selectivity requirements of distribution line protection can be met.