Digital configuration of substation is a complex process. Frequently modifying configuration file leads to inefficiency, difficulty in supervision, over-reliance on personnel quality and high risk in practical application. On the basis of in-depth analysis of the adaptability of blockchain technology to solve substation configuration problems, a substation configuration version management framework based on blockchain is designed, and the key parts, such as block structure of data layer, organization of network layer, mechanism of consensus layer, implementation of smart contract layer, operation flow, reclaiming disk space, statistics and supervision, are designed in detail. Finally, the performance and safety of the design scheme are analyzed. The digital configuration version management of substation based on blockchain provides a distributed system scheme, and realizes automatic renewal based on smart contract and supervision with the characteristics of non-tampering and traceability. Its efficiency and security are guaranteed. It supplies a new solution for the engineering application of smart substation. This work is supported by National Key Research and Development Program of China (No. 2018YFB1500800).