Due to the direct conversion characteristics of the matrix converter, the output side performance is very susceptible to disturbance. A model-independent Auto Disturbance Rejection Controller (ADRC) is added to the matrix converter with indirect space vector modulation for its closed-loop control. Because the ADRC controller has many parameters in practical application and difficult to adjust parameters, it will affect the use of ADRC rejection controller in matrix converter system. In this paper, an Artificial Bee Colony (ABC) algorithm is used to optimize the parameters of ADRC in the closed-loop system of matrix converter. The algorithm performs global and local search at every time when finding the optimal value of fitness function, which avoids local optimum and has fast convergence speed. The relative artificial tuning parameters greatly improve the efficiency and accuracy. Experimental results show that using artificial ABC to optimize parameters can not only ensure the output voltage quality of matrix converter, but also improve the parameter tuning efficiency of ADRC, guaranteeing the ADRC being applied to the closed loop control of matrix converter. This work is supported by National Key Research and Development Program of China (No. 2016YFC0600906).