In order to achieve MPPT of photovoltaic cell, a method based on LSSVM for MPPT is proposed based on the analysis of the advantages and disadvantages of the existing methods. To verify the effectiveness of this method, the simulation model of photovoltaic cell is built in Matlab/Simulink, and the output characteristics of the photovoltaic cell are analyzed. The method based on LSSVM for MPPT is simulated using LSSVM toolbox, in which the cross-validation method is used to optimize the LSSVM parameters. The simulation results show that the method proposed can achieve the output voltage and current tracking at the maximum power point accurately. Compared with other methods, it can effectively avoid the system running in the shock at the maximum power point.